B-DNA: Dickerson's Dodecamer
Dickerson Dodecamer is a double stranded DNA with the following sequence
1) Highlight the Phosphate backbone. 2) Show antiparallel strands. 3) Space-filling model of the dodecamer. 4) Highlight individual bases. T A C G 5) Highlight donors and acceptors. A) The H-bonds acceptors in the groove are colored in yellow. B) The H-bonds donors in the groove are colored in green. C) The Thymine methyl group are colored in magenta. 6) Highlight a C-G nucleotide pair. 7) Highlight propeller twist One of the characteristics of B-DNA is the propeller twist in which two bases in a basepair are rotated in such a way that are not in the same plane. 8) Highlight the sugar pucker. References H.R. Drew, R.M. Wing, T. Nakano, C. Broka, S. Tanaka, K. Itakura, R. E. Dickerson. STRUCTURE OF A B-DNA DODECAMER. CONFORMATION AND DYNAMICS PROC.NAT.ACAD.SCI.USA V. 78 2179 1981 PDB CODE=156D
2) Show antiparallel strands. 3) Space-filling model of the dodecamer.
4) Highlight individual bases. T A C G 5) Highlight donors and acceptors. A) The H-bonds acceptors in the groove are colored in yellow. B) The H-bonds donors in the groove are colored in green. C) The Thymine methyl group are colored in magenta. 6) Highlight a C-G nucleotide pair. 7) Highlight propeller twist One of the characteristics of B-DNA is the propeller twist in which two bases in a basepair are rotated in such a way that are not in the same plane. 8) Highlight the sugar pucker. References H.R. Drew, R.M. Wing, T. Nakano, C. Broka, S. Tanaka, K. Itakura, R. E. Dickerson. STRUCTURE OF A B-DNA DODECAMER. CONFORMATION AND DYNAMICS PROC.NAT.ACAD.SCI.USA V. 78 2179 1981 PDB CODE=156D
5) Highlight donors and acceptors. A) The H-bonds acceptors in the groove are colored in yellow.
B) The H-bonds donors in the groove are colored in green.
C) The Thymine methyl group are colored in magenta.
6) Highlight a C-G nucleotide pair. 7) Highlight propeller twist One of the characteristics of B-DNA is the propeller twist in which two bases in a basepair are rotated in such a way that are not in the same plane. 8) Highlight the sugar pucker. References H.R. Drew, R.M. Wing, T. Nakano, C. Broka, S. Tanaka, K. Itakura, R. E. Dickerson. STRUCTURE OF A B-DNA DODECAMER. CONFORMATION AND DYNAMICS PROC.NAT.ACAD.SCI.USA V. 78 2179 1981 PDB CODE=156D
7) Highlight propeller twist One of the characteristics of B-DNA is the propeller twist in which two bases in a basepair are rotated in such a way that are not in the same plane. 8) Highlight the sugar pucker. References H.R. Drew, R.M. Wing, T. Nakano, C. Broka, S. Tanaka, K. Itakura, R. E. Dickerson. STRUCTURE OF A B-DNA DODECAMER. CONFORMATION AND DYNAMICS PROC.NAT.ACAD.SCI.USA V. 78 2179 1981 PDB CODE=156D
8) Highlight the sugar pucker. References H.R. Drew, R.M. Wing, T. Nakano, C. Broka, S. Tanaka, K. Itakura, R. E. Dickerson. STRUCTURE OF A B-DNA DODECAMER. CONFORMATION AND DYNAMICS PROC.NAT.ACAD.SCI.USA V. 78 2179 1981 PDB CODE=156D
References H.R. Drew, R.M. Wing, T. Nakano, C. Broka, S. Tanaka, K. Itakura, R. E. Dickerson. STRUCTURE OF A B-DNA DODECAMER. CONFORMATION AND DYNAMICS PROC.NAT.ACAD.SCI.USA V. 78 2179 1981
PDB CODE=156D