Z-DNA:
5'-CGCGCG-3' 3'-CGCGCG-5'
1) Highlight the Phosphate backbone. 2) Space-filling model of the Z-DNA. 3) Highlight donors and acceptors. A) The H-bonds acceptors in the groove are colored in yellow. B) The H-bonds donors in the groove are colored in green. D) Remove one of the strands of the dodecamer. 4) Highlight the alternating up-down O4' of the sugar backbone. 5) Display central CpG step. 6) Display a C-G pair. Note syn G, c3' endo sugar; anti C, c2' endo sugar References J.Wang,G.J.Quigley,F.J.Kolpak,J.L.Crawford, J.H.Van Boom,G.Van Der Marel,A.Rich Molecular Structure of a Left-Handed Double Helical DNA Fragment at Atomic Resolution NATURE V. 282 680 1979 PDB CODE=2DCG
2) Space-filling model of the Z-DNA.
3) Highlight donors and acceptors. A) The H-bonds acceptors in the groove are colored in yellow.
B) The H-bonds donors in the groove are colored in green.
D) Remove one of the strands of the dodecamer.
4) Highlight the alternating up-down O4' of the sugar backbone.
5) Display central CpG step.
6) Display a C-G pair. Note syn G, c3' endo sugar; anti C, c2' endo sugar References J.Wang,G.J.Quigley,F.J.Kolpak,J.L.Crawford, J.H.Van Boom,G.Van Der Marel,A.Rich Molecular Structure of a Left-Handed Double Helical DNA Fragment at Atomic Resolution NATURE V. 282 680 1979 PDB CODE=2DCG
References
J.Wang,G.J.Quigley,F.J.Kolpak,J.L.Crawford, J.H.Van Boom,G.Van Der Marel,A.Rich Molecular Structure of a Left-Handed Double Helical DNA Fragment at Atomic Resolution NATURE V. 282 680 1979 PDB CODE=2DCG