Protein
|
Fibril Origins
|
Residues Ordered
|
Method
|
Resol- ution (Å)
|
Polarity Map
|
Energy Map
|
PDB ID
|
Reference
|
α-synuclein
| Recombinant
| 43-83
| cryoEM
| 3.6
|  |
 |
6cu8
|
Li et al., 2018
|
α-synuclein wt
| Recombinant
| 43-97
| ssNMR
| N/A
|  |
 |
2n0a
|
Tuttle et al., 2016
|
α-synuclein Type 3 Filaments
| Recombinant, seeded from Multiple System Atrophy Case 5
| 36-99
| cryoEM
| 3.18
|  |
 |
7nck
|
Lövestam et al., 2021
|
α-synuclein H50Q
| Recombinant
| 36-99
| cryoEM
| 3.3
|  |
 |
6peo
|
Boyer et al., 2019
|
α-synuclein H50Q
| Recombinant
| 36-99
| cryoEM
| 3.6
|  |
 |
6pes
|
Boyer et al., 2019
|
α-synuclein A53T
| Recombinant
| 37-99
| cryoEM
| 3.5
|  |
 |
6lrq
|
Sun et al., 2020
|
α-synuclein N-acetylated, 1-103
| Recombinant
| 37-96
| cryoEM
| 3.4
|  |
 |
6osm
|
Ni et al., 2019
|
α-synuclein
| Recombinant, human, complex with ligand F0502B
| 37-97
| cryoEM
| 2.6
|  |
 |
7wmm
|
Tao et al., 2023
|
α-synuclein rod polymorph
| Recombinant, human
| 38-97
| cryoEM
| 3.5
|  |
 |
6cu7
|
Li et al., 2018
|
α-synuclein N-acetylated, 1-122
| Recombinant, human
| 39-97
| cryoEM
| 3.0
|  |
 |
6osl
|
Ni et al., 2019
|
α-synuclein N-acetylated, 1-140
| Recombinant, human
| 37-97
| cryoEM
| 2.8
|  |
 |
6osj
|
Ni et al., 2019
|
α-synuclein N-acetylated, 1-140,
| Recombinant, human
| 37-99
| cryoEM
| 3.07
|  |
 |
6a6b
|
Li et al., 2018
|
α-synuclein (1-121)
| Recombinant
| 38-95
| cryoEM
| 3.4
|  |
 |
6h6b
|
Guerrero-Ferreira et al., 2018
|
α-synuclein
| Recombinant, human, heparin-remodeled
| 37-94
| cryoEM
| 3.50
|  |
 |
7v4d
|
Fan et al., 2022
|
α-synuclein
| Recombinant, human, seeded from a Parkinson's Disease patient, postmortem, filament type 4
| 36-95
| cryoEM
| 3.40
|  |
 |
7v49
|
Fan et al., 2022
|
α-synuclein
| Recombinant, human, seeded from a Parkinson's Disease patient, postmortem, minor polymorph
| 36-95
| cryoEM
| 3.40
|  |
 |
8h05
|
Fan et al., 2022
|
α-synuclein
| Human, extracted from Multiple System Atrophy Case 2, Type II-2 fibril
| 14-99
| cryoEM
| 3.1
|  |
 |
6xyq
|
Schweighauser et al., 2020
|
α-synuclein
| Human, extracted from Multiple System Atrophy brain, Case 2, Type II-1 fibril
| 14-99
| cryoEM
| 3.3
|  |
 |
6xyp
|
Schweighauser et al., 2020
|
α-synuclein
| Human, extracted from Multiple System Atrophy brain, Case 1, Type I fibril
| 14-99
| cryoEM
| 2.6
|  |
 |
6xyo
|
Schweighauser et al., 2020
|
α-synuclein E46K
| Recombinant
| 45-99
| cryoEM
| 3.37
|  |
 |
6l4s
|
Zhao et al., 2020a
|
α-synuclein wild type
| Recombinant, seeded with E46K hereditary mutation
| 46-96
| cryoEM
| 3.8
|  |
 |
7c1d
|
Long et al., 2021
|
α-synuclein G51D hereditary mutation
| Recombinant
| 50-98
| cryoEM
| 3.02
|  |
 |
7e0f
|
Sun et al., 2021
|
α-synuclein
| Recombinant, human, recombinant, heparin-induced, polymorph 4
| 37-98
| cryoEM
| 3.30
|  |
 |
7v4c
|
Fan et al., 2022
|
α-synuclein
| Recombinant, human, recombinant, heparin-induced, polymorph 1
| 14-25, 32-99
| cryoEM
| 3.20
|  |
 |
7v4a
|
Fan et al., 2022
|
α-synuclein polymorph 2b
| Recombinant
| 14-25, 36-96
| cryoEM
| 3.4
|  |
 |
6sst
|
Guerrero-Ferreira et al., 2019
|
α-synuclein polymorph 2b
| Recombinant
| 9-24, 35-93
| cryoEM
| 3.5
|  |
 |
6rtb
|
Guerrero-Ferreira et al., 2019
|
α-synuclein Type 2A Filaments
| Recombinant, seeded from Multiple System Atrophy Case 2
| 37-97
| cryoEM
| 3.43
|  |
 |
7ncg
|
Lövestam et al., 2021
|
α-synuclein Type 2B Filaments
| Recombinant, seeded from Multiple System Atrophy Case 1
| 14-25, 36-91
| cryoEM
| 3.55
|  |
 |
7nci
|
Lövestam et al., 2021
|
α-synuclein Type 2AB Filaments
| Recombinant, seeded from Multiple System Atrophy Case 1
| 37-97
| cryoEM
| 4.23
|  |
 |
7ncj
|
Lövestam et al., 2021
|
α-synuclein
| Recombinant, seeded from Multiple System Atrophy
| 36-93
| cryoEM
| 3.02
|  |
 |
7ozh
|
Frieg et al., 2022
|
α-synuclein
| Recombinant, human, seeded from a Parkinson's Disease patient, mid-to-late stage 1, major polymorph
| 36-97
| cryoEM
| 3.00
|  |
 |
7xo1
|
Fan et al., 2022
|
α-synuclein
| Recombinant, human, seeded from a Parkinson's Disease patient, mid-to-late stage 4, filament type 1C
| 36-98
| cryoEM
| 2.60
|  |
 |
7xo3
|
Fan et al., 2022
|
α-synuclein
| Recombinant, human, seeded from a Parkinson's Disease patient, preclinical, filament type 1A
| 36-96
| cryoEM
| 2.80
|  |
 |
7v47
|
Fan et al., 2022
|
α-synuclein
| Recombinant, human, seeded from Parkinson's Disease patient, preclinical, major polymorph
| 36-96
| cryoEM
| 2.80
|  |
 |
8h03
|
Fan et al., 2022
|
α-synuclein
| Recombinant, human, seeded from a Parkinson's Disease patient, postmortem, filament type 1D
| 36-98
| cryoEM
| 3.00
|  |
 |
7v48
|
Fan et al., 2022
|
α-synuclein
| Recombinant, human, seeded from a Parkinson's Disease patient postmortem, major polymorph
| 36-98
| cryoEM
| 3.00
|  |
 |
8h04
|
Fan et al., 2022
|
α-synuclein
| Recombinant, human, recombinant, heparin-induced, polymorph 3
| 14-25, 32-99
| cryoEM
| 3.10
|  |
 |
7v4b
|
Fan et al., 2022
|
α-synuclein polymorph 2a
| Recombinant
| 14-25, 36-95
| cryoEM
| 3.1
|  |
 |
6rt0
|
Guerrero-Ferreira et al., 2019
|
α-synuclein polymorph 2a
|
Recombinant
|
14-25, 36-96
|
cryoEM
|
3.0
|
 |
 |
6ssx
|
Guerrero-Ferreira et al., 2019
|
α-synuclein E46K
|
Recombinant
|
36-98
|
cryoEM
|
2.5
|
 |
 |
6ufr
|
Boyer et al., 2020
|
α-synuclein Type 1A Filaments
| Recombinant, seeded from Multiple System Atrophy Case 2
| 37-97
| cryoEM
| 3.47
|  |
 |
7nca
|
Lövestam et al., 2021
|
α-synuclein
| Recombinant, human, seeded from a Parkinson's Disease patient, mid-to-late stage 1, minor polymorph
| 36-97
| cryoEM
| 3.00
|  |
 |
7xo0
|
Fan et al., 2022
|
α-synuclein
| Recombinant, human, seeded from a Parkinson's Disease patient, mid-to-late stage 4, minor polymorph
| 36-97
| cryoEM
| 3.00
|  |
 |
7xo2
|
Fan et al., 2022
|
α-synuclein Type 1B Filaments
| Recombinant, seeded from Multiple System Atrophy Case 1
| 14-25, 36-91
| cryoEM
| 3.84
|  |
 |
7nch
|
Lövestam et al., 2021
|
α-synuclein
| Recombinant, seeded from brain of Parkinson's Disease Patient
| 14-25,36-96
| cryoEM
| 3.30
|  |
 |
7ozg
|
Frieg et al., 2022
|
α-synuclein, human
| Recombinant, Lipidic, Polymorph L2B
| 14-24,33-96
| cryoEM
| 3.05
|  |
 |
8ads
|
Frieg et al., 2022b
|
α-synuclein, human
| Recombinant, Lipidic, Polymorph L1A
| 1-99
| cryoEM
| 3.24
|  |
 |
8adu
|
Frieg et al., 2022b
|
α-synuclein, human
| Recombinant, Lipidic, Polymorph L1B
| 1-99
| cryoEM
| 2.98
|  |
 |
8adv
|
Frieg et al., 2022b
|
α-synuclein, human
| Recombinant, Lipidic, Polymorph L1C
| 1-99
| cryoEM
| 2.95
|  |
 |
8adw
|
Frieg et al., 2022b
|
α-synuclein, human
| Recombinant, Lipidic, Polymorph L3A
| 14-19,33-97
| cryoEM
| 2.76
|  |
 |
8aex
|
Frieg et al., 2022b
|
α-synuclein
| human, recombinant, heparin-remodeled, lipidic polymorph L2A
| 14-24, 33-96
| cryoEM
| 3.22
|  |
 |
8a4l
|
Frieg et al., 2022
|
α-synuclein
| Human, extracted from Parkinson's Disease Dementia patient brain; identical fold as Parkinson's Disease and Dementia with Lewy bodies
| 14-22, 31-100
| cryoEM
| 2.16
|  |
 |
8a9l
|
Yang et al., 2022
|
α-synuclein phospho-Y39 twist-dimer
| Semisynthetic
| 1-100
| cryoEM
| 3.22
|  |
 |
6l1t
|
Zhao et al., 2020b
|
α-synuclein phospho-Y39 twist-trimer
| Semisynthetic
| 1-100
| cryoEM
| 3.37
|  |
 |
6l1u
|
Zhao et al., 2020b
|
α-synuclein N-terminal Truncation 41-140
| Recombinant
| 46-96
| cryoEM
| 3.2
|  |
 |
7lc9
|
McGlinchey et al., 2021
|
α-synuclein Filaments
| Recombinant, formed in the presence of Tau
| 37-79
| cryoEM
| 4.00
|  |
 |
7l7h
|
Hojjatian et al., 2021
|
Amyloid-β(1-42)
| Recombinant
| 17-42
| ssNMR
| N/A
|  |
 |
2beg
|
Lührs et al., 2005
|
Amyloid-β(1-40) Iowa Mutation D23N
| Recombinant
| 15-40
| ssNMR
| N/A
|  |
 |
2lnq
|
Qiang et al., 2012
|
Amyloid-β(1-40) (+)stagger
| Recombinant
| 9-40
| ssNMR
| N/A
|  |
 |
2lmn
|
Paravastu et al., 2008
|
Amyloid-β(1-40) (-)stagger
| Recombinant
| 9-40
| ssNMR
| N/A
|  |
 |
2lmo
|
Paravastu et al., 2008
|
Amyloid-β(1-40) (+)stagger
| Recombinant
| 9-40
| ssNMR
| N/A
|  |
 |
2lmp
|
Paravastu et al., 2008
|
Amyloid-β(1-40) (-)stagger
| Recombinant
| 9-40
| ssNMR
| N/A
|  |
 |
2lmq
|
Paravastu et al., 2008
|
Amyloid-β(1-40) Iowa Mutation D23N
| Recombinant
| 15-40
| ssNMR
| N/A
|  |
 |
2mpz
|
Sgourakis et al., 2015
|
Amyloid-β(1-40)
| Recombinant, seeded from brain of a human with Alzheimers Disease
| 1-40
| ssNMR
| N/A
|  |
 |
2m4j
|
Lu et al., 2013
|
Amyloid-β(1-42)
| Recombinant
| 16-40
| CryoEM
| 5.0
|  |
 |
5aef
|
Schmidt et al., 2015
|
Amyloid-β(20-34)(L-isoAsp23)
| Synthetic
| 20-34
| MicroED
| 1.1
|  |
 |
6nb9
|
Warmack et al., 2019
|
Amyloid-β(20-34)
| Synthetic
| 20-34
| MicroED
| 1.1
|  |
 |
6oiz
|
Warmack et al., 2019
|
Amyloid-β(1-42)
| Recombinant
| 11-42
| ssNMR
| N/A
|  |
 |
2mxu
|
Xiao et al., 2015
|
Amyloid-β(1-42)
| Recombinant
| 14-42
| ssNMR
| N/A
|  |
 |
5kk3
|
Colvin et al., 2016
|
Amyloid-β(1-42)
| Recombinant
| 14-42
| ssNMR
| N/A
|  |
 |
2nao
|
Wälti et al., 2016
|
Amyloid-β(1-40) E22Δ Osaka mutation
| Recombinant
| 1-40
| ssNMR
| N/A
|  |
 |
2mvx
|
Schütz et al., 2015
|
Amyloid-β(1-42)
|
Recombinant
|
1-42
|
cryoEM
|
4.0
|
 |
 |
5oqv
|
Gremer et al., 2017
|
Amyloid-β
|
Extracted from brain of a human with Alzheimers Disease (meningeal tissue)
|
1-40
|
cryoEM
|
4.4
|
 |
 |
6shs
|
Kollmer et al., 2019
|
Amyloid-β(1-40)
| Seeded with fibrils extracted from brain of a human with Alzheimers Disease (cortical tissue)
| 10-40
| cryoEM
| 2.77
|  |
 |
6w0o
|
Ghosh et al., 2021
|
Amyloid-β(1-40)
|
Recombinant
|
11-40
|
ssNMR
|
N/A
|
 |
 |
6ti5
|
Cerofolini et al., 2020
|
Amyloid-β(1-40 and 1-42 co-fibril)
| Human, recombinant
| 11-40, 11-42
| ssNMR
| N/A
|  |
 |
6ti6
|
Cerofolini et al., 2020
|
Amyloid-β(1-42), human
| Extracted from the brain of a patient with Alzheimers Disease, type I filaments
| 9-42
| cryoEM
| 2.5
|  |
 |
7q4b
|
Yang et al., 2022
|
Amyloid-β(1-42), human
| Aqueous extracts from the brain of a patient with Alzheimers Disease, type I filaments
| 9-42
| cryoEM
| 2.9
|  |
 |
8azs
|
Stern et al., 2022
|
Amyloid-β(1-42), human
| Extracted from the brain of a patient with Alzheimers Disease, type II filaments
| 12-42
| cryoEM
| 2.8
|  |
 |
7q4m
|
Yang et al., 2022
|
Amyloid-β(1-42), human
| Aqueous extracts from the brain of a patient with Alzheimers Disease, type II filaments
| 12-42
| cryoEM
| 3.7
|  |
 |
8azt
|
Stern et al., 2022
|
Amyloid-β(1-42)
| Synthetic, glycosylated at Tyr10
| 6-42
| cryoEM
| 3.10
|  |
 |
7f29
|
Liu et al., 2021
|
Antimicrobial peptide uperin 3.5
| Synthetic, Mjobergs toadlet
| 1-17
| cryoEM
| 3.0
|  |
 |
7qv5
|
Bücker et al., 2022
|
Antimicrobial peptide aurein 3.3
| Synthetic, blue-thighed tree frog
| 1-17
| cryoEM
| 3.5
|  |
 |
7qv6
|
Bücker et al., 2022
|
β-2-microglobulin
| Recombinant
| 22-85
| cryoEM
| 3.9
|  |
 |
6gk3
|
Iadanza et al., 2018
|
β-2-microglobulin
|
Recombinant
|
20-41
|
ssNMR
|
N/A
|
 |
 |
2e8d
|
Iwata et al., 2006
|
β-endorphin
|
Recombinant
|
1-31
|
ssNMR
|
N/A
|
 |
 |
6tub
|
Seuring et al., 2020
|
CA150 WW2 Domain
| Recombinant
| 3-33
| ssNMR
| N/A
|  |
 |
2nnt
|
Ferguson et al., 2006
|
FUS LC Domain
| Recombinant
| 37-97
| ssNMR
| N/A
|  |
 |
5w3n
|
Murray et al., 2017
|
FUS LC Domain
| Recombinant
| 112-150
| cryoEM
| 2.62
|  |
 |
6xfm
|
Lee et al., 2021
|
FUS LC Domain
| Recombinant
| 34-124
| cryoEM
| 2.9
|  |
 |
7vqq
|
Sun et al., 2021
|
Glucagon
| Synthetic
| 1-29
| ssNMR
| N/A
|  |
 |
6nzn
|
Gelenter et al., 2019
|
HET-s (218-289)
| Recombinant
| 224-283
| ssNMR
| N/A
|  |
 |
2rnm
|
Wasmer et al., 2008
|
hnRNPA1
| Recombinant
| 251-295
| cryoEM
| 2.8
|  |
 |
7bx7
|
Sun et al., 2020
|
hnRNPA2
| Recombinant
| 251-295
| cryoEM
| 3.1
|  |
 |
6wqk
|
Lu et al., 2020
|
Islet Amyloid Polypeptide (IAPP), human, SUMO-tagged
| Recombinant
| 14-37
| cryoEM
| 3.7
|  |
 |
6vw2
|
Cao et al., 2020
|
Islet Amyloid Polypeptide (IAPP), amidated, wild type
| Synthetic, seeded with fibrils from a Type 2 Diabetes Patient, Polymorph 2
| 6-37
| cryoEM
| 3.9
|  |
 |
7m62
|
Cao et al., 2021
|
Islet Amyloid Polypeptide (IAPP), amidated, wild type
| Synthetic, seeded with fibrils from a Type 2 Diabetes Patient, Polymorph 3
| 13-37
| cryoEM
| 4.0
|  |
 |
7m64
|
Cao et al., 2021
|
Islet Amyloid Polypeptide (IAPP) C-term amidated
| Human, synthetic
| 13-37
| cryoEM
| 4.2
|  |
 |
6y1a
|
Röder et al., 2020
|
Islet Amyloid Polypeptide (IAPP) C-term amidated
| Synthetic
| 13-37
| cryoEM
| 3.6
|  |
 |
6zrf
|
Gallardo et al., 2020
|
Islet Amyloid Polypeptide (IAPP), amidated, wild type
| Synthetic, seeded with fibrils from a Type 2 Diabetes Patient, Polymorph 1
| 13-37
| cryoEM
| 3.8
|  |
 |
7m61
|
Cao et al., 2021
|
Islet Amyloid Polypeptide (IAPP) C-term amidated S20G mutant
| Synthetic
| 15-37
| cryoEM
| 3.9
|  |
 |
6zrq
|
Gallardo et al., 2020
|
Islet Amyloid Polypeptide (IAPP) C-term amidated S20G mutant
| Synthetic
| 15-37
| cryoEM
| 4.0
|  |
 |
6zrr
|
Gallardo et al., 2020
|
Islet Amyloid Polypeptide (IAPP), amidated, wild type
| Synthetic, seeded with fibrils from a Type 2 Diabetes Patient, Polymorph 4
| 6-37
| cryoEM
| 4.1
|  |
 |
7m65
|
Cao et al., 2021
|
Light Chain λ1, Antibody, human
| Extracted from heart of a patient with cardiac AL amyloidosis
| 15-105
| cryoEM
| 4.0
|  |
 |
6ic3
|
Radamaker et al., 2019
|
Light Chain λ3, Antibody, human
| Extracted from heart of a patient with cardiac AL amyloidosis, conformation A
| 9-49, 60-107
| cryoEM
| 3.2
|  |
 |
6z1o
|
Radamaker et al., 2021
|
Light Chain λ3, Antibody, human
| Extracted from heart of a patient with cardiac AL amyloidosis, conformation B
| 9-49, 68-107
| cryoEM
| 3.4
|  |
 |
6z1i
|
Radamaker et al., 2021
|
Light Chain λ6, Antibody, human
| Extracted from heart of a patient with amyloid cardiomyopathy
| 1-37, 66-105
| cryoEM
| 3.3
|  |
 |
6hud
|
Swuec et al., 2019
|
Nup98, human
| Recombinant, polymorph 1
| 85-124
| cryoEM
| 2.76
|  |
 |
7q64
|
Ibáñez de Opakua et al., 2022
|
Nup98, human
| Recombinant, polymorph 2
| 85-124
| cryoEM
| 3.32
|  |
 |
7q65
|
Ibáñez de Opakua et al., 2022
|
Nup98, human
| Recombinant, polymorph 3
| 85-121
| cryoEM
| 2.79
|  |
 |
7q66
|
Ibáñez de Opakua et al., 2022
|
Nup98, human
| Recombinant, polymorph 4
| 87-119
| cryoEM
| 3.37
|  |
 |
7q67
|
Ibáñez de Opakua et al., 2022
|
Orb2, Drosophila
|
Extracted from Drosophila brain
|
176-206
|
cryoEM
|
2.6
|
 |
 |
6vps
|
Hervás et al., 2020
|
Prion Protein, human
| Recombinant
| 106-145
| cryoEM
| 3.5
|  |
 |
6uur
|
Glynn et al., 2020
|
Prion Protein, human, V129, F198S
| Extracted from patient with Gerstmann-Sträussler-Scheinker disease, type I filament
| 80-141
| cryoEM
| 3.29
|  |
 |
7umq
|
Hallinan et al., 2022
|
Prion Protein, human, V129, F198S
| Extracted from patient with Gerstmann-Sträussler-Scheinker disease, type IIb filament
| 80-141
| cryoEM
| 3.13
|  |
 |
7un5
|
Hallinan et al., 2022
|
Prion Protein, human
| Recombinant
| 170-229
| cryoEM
| 2.7
|  |
 |
6lni
|
Wang et al., 2020
|
Prion Protein, human, E196K Inherited Mutation
| Recombinant
| 175-217
| cryoEM
| 3.07
|  |
 |
7dwv
|
Wang et al., 2021
|
Prion Protein, mouse, PrP23-144
| Recombinant, polymorph 1
| 108-141
| cryoEM
| 3.92
|  |
 |
8dja
|
Li et al., 2022
|
Prion Protein, human, Y145Stop mutation
| Recombinant
| 108-141
| cryoEM
| 2.86
|  |
 |
7rl4
|
Li et al., 2022
|
Prion Protein, Syrian hamster
| Recombinant, prepared in acidic solution
| 119-143
| cryoEM
| 2.20
|  |
 |
7yat
|
Chen et al., 2022
|
Prion Protein, Syrian hamster, infectious, 263K strain
| Extracted from clinically ill hamster brain
| 95-227
| cryoEM
| 3.14
|  |
 |
7lna
|
Kraus et al., 2021
|
Prion Protein, mouse, anchorless, aRML prion strain, infectious
| Extracted from brains of terminally ill mice
| 93-230
| cryoEM
| 3.00
|  |
 |
7td6
|
Hoyt et al., 2022
|
Prion Protein, mouse, anchorless, aRML prion strain, infectious
| Extracted from brains of terminally ill mice
| 94-225
| cryoEM
| 2.70
|  |
 |
7qig
|
Manka et al., 2022
|
Prion Protein, mouse, a22L prion strain, infectious
| Extracted from brains of terminally ill mice
| 94-226
| cryoEM
| 3.20
|  |
 |
8efu
|
Hoyt et al., 2022
|
RIPK1(496-583) + RIPK3(388-518), human
| Recombinant
| 448-462, 532-549
| ssNMR
| N/A
|  |
 |
5v7z
|
Mompeán et al., 2018
|
RIPK3(388-518) human
| Recombinant
| 448-469
| cryoEM
| 4.24
|  |
 |
7da4
|
Wu et al., 2021
|
RIPK3(418-518) human
| Recombinant
| 447-475
| ssNMR
| N/A
|  |
 |
7dac
|
Wu et al., 2021
|
Serum Amyloid A, mouse
| Extracted from spleen of a mouse with systemic AA amyloidosis, morphology I
| 1-69
| cryoEM
| 3.0
|  |
 |
6dso
|
Liberta et al., 2019
|
Serum Amyloid A, mouse
| Recombinant, seeded by ex vivo fibrils from mouse liver, morphology I
| 1-69
| cryoEM
| 2.69
|  |
 |
7ovt
|
Heerde et al., 2022
|
Serum Amyloid A, mouse
| Extracted from spleen of a mouse with systemic AA amyloidosis, morphology II
| 1-69
| cryoEM
| 3.5
|  |
 |
6zch
|
Bansal et al., 2021
|
Serum Amyloid A, mouse
|
Recombinant, unseeded, in vitro morphology i
|
1-37
|
cryoEM
|
2.73
|
 |
 |
6zcf
|
Bansal et al., 2021
|
Serum Amyloid A, mouse
|
Recombinant, unseeded, in vitro morphology ii
|
1-37
|
cryoEM
|
2.95
|
 |
 |
6zcg
|
Bansal et al., 2021
|
Serum Amyloid A, human
| Extracted from kidney of a human with AA amyloidosis, glomerular variant
| 2-55
| cryoEM
| 2.7
|  |
 |
6mst
|
Liberta et al., 2019
|
Serum Amyloid A, human
| Extracted from kidney of a human with AA amyloidosis, vascular variant
| 2-69
| cryoEM
| 2.56
|  |
 |
7zky
|
Banerjee et al., 2022
|
Serum Amyloid A, feline
| Extracted from kidney of a domestic short hair cat with AA amyloidosis
| 19-94
| cryoEM
| 3.30
|  |
 |
7zh7
|
Schulte et al., 2022
|
SH3 Domain of PI3-kinase
| Recombinant
| 1-77
| cryoEM
| 3.4
|  |
 |
6r4r
|
Röder et al., 2019
|
Superoxide Dismutase
| Recombinant, full-length
| 3-55, 86-153
| cryoEM
| 2.95
|  |
 |
7vzf
|
Wang et al., 2022
|
Tau 3R+4R, Alzheimer's, Paired Helical Filament
| Extracted from brain of a human with Alzheimer's Disease
| 306-378
| cryoEM
| 3.4
|  |
 |
5o3l
|
Fitzpatrick et al., 2017
|
Tau 3R+4R Paired Helical Filament
| Extracted from Alzheimers Patient Brain and Stained with PET ligand APN1607
| 304-380
| cryoEM
| 3.00
|  |
 |
7nrv
|
Shi et al., 2021
|
Tau 3R+4R Paired Helical Filament
| Extracted from Alzheimers Patient Brain and Soaked with EGCG for 0 hours
| 304-379
| cryoEM
| 3.40
|  |
 |
7upe
|
Seidler et al., 2022
|
Tau 3R+4R Paired Helical Filament
| Extracted from Alzheimers Patient Brain and Soaked with EGCG for 1 hour
| 306-379
| cryoEM
| 3.30
|  |
 |
7upf
|
Seidler et al., 2022
|
Tau 3R+4R Paired Helical Filament
| Extracted from Alzheimers Patient Brain and Soaked with EGCG for 3 hours
| 306-379
| cryoEM
| 3.80
|  |
 |
7upg
|
Seidler et al., 2022
|
Tau 3R+4R Paired Helical Filament
| Extracted from PrP Cerebral Amyloid Angiopathy Patient Brain
| 306-378
| cryoEM
| 3.00
|  |
 |
7mkf
|
Hallinan et al., 2021
|
Tau 3R+4R Paired Helical Filament
| Extracted from Gerstmann-Sträussler-Scheinker Patient Brain
| 305-379
| cryoEM
| 3.30
|  |
 |
7mkh
|
Hallinan et al., 2021
|
Tau 3R+4R Paired Helical Filament
| Extracted from Primary Age-Related Tauopathy Patient Brain Case 3
| 304-380
| cryoEM
| 2.76
|  |
 |
7nrq
|
Shi et al., 2021
|
Tau (297-391)
| Recombinant, PHF-like polymorph, 200 mM MgCl2, 200 rpm, filament type 4a
| 304-379
| cryoEM
| 3.20
|  |
 |
7ql4
|
Lövestam et al., 2022
|
Tau (266-391) and 3R/(297-391)
| Recombinant, PHF-like polymorph
| 304-379
| cryoEM
| 3.46
|  |
 |
7ymn
|
Li et al., 2022
|
Tau (297-391)
| Recombinant, AD-like fold, LiCl, filament type 2c
| 304-378
| cryoEM
| 3.29
|  |
 |
7qjv
|
Lövestam et al., 2022
|
Tau 3R+4R, Alzheimer's, Straight Filament
| Extracted from brain of a human with Alzheimer's Disease
| 306-378
| cryoEM
| 3.4
|  |
 |
5o3t
|
Fitzpatrick et al., 2017
|
Tau 3R+4R Straight Filament
| Extracted from Alzheimers Patient Brain and Stained with PET ligand APN1607
| 304-380
| cryoEM
| 3.55
|  |
 |
7nrx
|
Shi et al., 2021
|
Tau 3R+4R Straight Filament
| Extracted from PrP Cerebral Amyloid Angiopathy Patient Brain
| 306-378
| cryoEM
| 3.07
|  |
 |
7mkg
|
Hallinan et al., 2021
|
Tau 3R+4R Straight Filament Conformation 1
| Extracted from Primary Age-Related Tauopathy Patient Brain Case 3
| 304-380
| cryoEM
| 2.68
|  |
 |
7nrs
|
Shi et al., 2021
|
Tau 3R+4R Straight Filament Conformation 2
| Extracted from Primary Age-Related Tauopathy Patient Brain Case 3
| 304-380
| cryoEM
| 2.68
|  |
 |
7nrt
|
Shi et al., 2021
|
Tau (297-408) S396D, S400D, T403D
| Recombinant, filament type 42a
| 304-379
| cryoEM
| 3.13
|  |
 |
7qki
|
Lövestam et al., 2022
|
Tau (258-391)
| Recombinant, phosphoglycerate, 700rpm, filament type 39a
| 304-379
| cryoEM
| 2.80
|  |
 |
7qkk
|
Lövestam et al., 2022
|
Tau (266-391)(297-391)
| Recombinant, MgCl2 and NaCl, filament type 14a
| 304-379
| cryoEM
| 2.57
|  |
 |
7qku
|
Lövestam et al., 2022
|
Tau (266-391)(297-391)
| Recombinant, KCl, filament type 10b
| 305-388
| cryoEM
| 2.59
|  |
 |
7r5h
|
Lövestam et al., 2022
|
Tau 4R, CTE Type I
| Extracted from brain of a patient with Chronic Traumatic Encephalopathy
| 305-379
| cryoEM
| 2.3
|  |
 |
6nwp
|
Falcon et al., 2019
|
Tau 4R, CTE Type I
| Extracted from brain of a patient with Chronic Traumatic Encephalopathy, complex with PET ligand flortaucipir
| 305-379
| cryoEM
| 2.6
|  |
 |
8byn
|
Shi et al., 2022
|
Tau 4R, CTE Type II
| Extracted from brain of a patient with Chronic Traumatic Encephalopathy
| 305-379
| cryoEM
| 3.4
|  |
 |
6nwq
|
Falcon et al., 2019
|
Tau (297-391)
| Recombinant, CTE type II-like polymorph, filament type 8a
| 305-379
| cryoEM
| 2.81
|  |
 |
7qjw
|
Lövestam et al., 2022
|
Tau (266-391)(297-391)
| Recombinant, CTE-like fold, MgSO4, NaCl, filament type 15b
| 306-378
| cryoEM
| 3.16
|  |
 |
7qkx
|
Lövestam et al., 2022
|
Tau (266-391)(297-391)
| Recombinant, CTE-like fold, MgSO4, NaCl, filament type 15c
| 306-377
| cryoEM
| 3.13
|  |
 |
7ql0
|
Lövestam et al., 2022
|
Tau (266-391)(297-391)
| Recombinant, CTE-like fold, MgSO4, NaCl, filament type 15a
| 309-377
| cryoEM
| 3.23
|  |
 |
7qkv
|
Lövestam et al., 2022
|
Tau (266-391)
| Recombinant, CTE-like fold, phosphate-buffered saline, filament type 23a
| 306-378
| cryoEM
| 3.34
|  |
 |
7ql1
|
Lövestam et al., 2022
|
Tau (266-391)(297-391)
| Recombinant, LiCl, filament type 9b
| 305-378
| cryoEM
| 3.40
|  |
 |
7qjz
|
Lövestam et al., 2022
|
Tau (266-391)(297-391)
| Recombinant, KCl, filament type 10a
| 306-379
| cryoEM
| 1.92
|  |
 |
7qk5
|
Lövestam et al., 2022
|
Tau (266-391)(297-391)
| Recombinant, NaCl, filament type 8b
| 308-378
| cryoEM
| 3.32
|  |
 |
7ql3
|
Lövestam et al., 2022
|
Tau (297-394)
| Recombinant, phosphate buffered saline, filament type 35d
| 305-379
| cryoEM
| 3.03
|  |
 |
7qk1
|
Lövestam et al., 2022
|
Tau (300-391)
| Recombinant, phosphate buffered saline, filament type 36a
| 308-378
| cryoEM
| 2.61
|  |
 |
7qk2
|
Lövestam et al., 2022
|
Tau (266-391)(297-391)
| Recombinant, MgCl2, NaCl, filament type 14b
| 305-379
| cryoEM
| 3.26
|  |
 |
7qkj
|
Lövestam et al., 2022
|
Tau (266-391)+(297-391)
| Recombinant, NaHCO3, NaCl, filament type 16a
| 304-379
| cryoEM
| 2.75
|  |
 |
7r4t
|
Lövestam et al., 2022
|
Tau (266-391)(297-391)
| Recombinant, LiCl, filament type 9a
| 305-379
| cryoEM
| 3.14
|  |
 |
7qjy
|
Lövestam et al., 2022
|
Tau (266-391)(297-391)
| Recombinant, ZnCl2, filament type 11a
| 304-379
| cryoEM
| 2.07
|  |
 |
7qkl
|
Lövestam et al., 2022
|
Tau (297-391)
| Recombinant, 700 rpm, filament type 34b
| 304-378
| cryoEM
| 2.99
|  |
 |
7qjx
|
Lövestam et al., 2022
|
Tau 3R
| Extracted from brain of a human with Pick's Disease
| 254-274, 305-378
| cryoEM
| 3.2
|  |
 |
6gx5
|
Falcon et al., 2018
|
Tau (297-391)
| Recombinant, spindle-like fold
| 304-362
| cryoEM
| 2.54
|  |
 |
7ypg
|
Li et al., 2022
|
Tau 4R
| Extracted from brain of a human with Corticobasal Degeneration (CBD), Filament Type I
| 274-380
| cryoEM
| 3.2
|  |
 |
6tjo
|
Zhang et al., 2020
|
Tau 4R
| Extracted from Argyrophilic Grain Disease (AGD) Patient Brain, Filament Type 1
| 273-387
| cryoEM
| 3.30
|  |
 |
7p6d
|
Shi et al., 2021
|
Tau 4R
| Extracted from brain of a human with Corticobasal Degeneration (CBD), Filament Type II
| 274-380
| cryoEM
| 3.0
|  |
 |
6tjx
|
Zhang et al., 2020
|
Tau 4R
| Extracted from Argyrophilic Grain Disease (AGD) Patient Brain, Filament Type 2
| 274-381
| cryoEM
| 3.40
|  |
 |
7p6e
|
Shi et al., 2021
|
Tau 4R
| Extracted from Progressive Supranuclear Palsy (PSP) Patient Brain
| 272-381
| cryoEM
| 2.70
|  |
 |
7p65
|
Shi et al., 2021
|
Tau 4R
| Extracted from Progressive Supranuclear Palsy (PSP) Patient Brain, Case 1
| 272-381
| cryoEM
| 4.20
|  |
 |
7u0z
|
Chang et al., 2022
|
Tau 4R
| Extracted from Globular Glial Tauopathy (GGT) Patient Brain, Filament Type 1
| 272-379
| cryoEM
| 3.00
|  |
 |
7p66
|
Shi et al., 2021
|
Tau 4R
| Extracted from Globular Glial Tauopathy (GGT) Patient Brain, filament type 2
| 272-379
| cryoEM
| 3.10
|  |
 |
7p67
|
Shi et al., 2021
|
Tau 4R
| Extracted from Globular Glial Tauopathy (GGT) Patient Brain, Filament Type 3
| 272-379
| cryoEM
| 2.90
|  |
 |
7p68
|
Shi et al., 2021
|
Tau 4R
| Extracted from Limbic-Predominant Neuronal Inclusion Body 4R Tauopathy (LNT) Patient Brain, Filament Type 1a
| 272-379
| cryoEM
| 1.90
|  |
 |
7p6a
|
Shi et al., 2021
|
Tau 4R
| Extracted from Limbic-Predominant Neuronal Inclusion Body 4R Tauopathy (LNT) Patient Brain, Filament Type 1b
| 272-379
| cryoEM
| 2.50
|  |
 |
7p6b
|
Shi et al., 2021
|
Tau 4R
| Extracted from Limbic-Predominant Neuronal Inclusion Body 4R Tauopathy (LNT) Patient Brain, Filament Type 2
| 272-379
| cryoEM
| 2.20
|  |
 |
7p6c
|
Shi et al., 2021
|
Tau40 and RNA
| Recombinant and grown with RNA
| 391-426
| cryoEM
| 3.40
|  |
 |
7sp1
|
Abskharon et al., 2022
|
Tau 0N4R with phosphoserine
| Recombinant, filament type 47a
| 376-441
| cryoEM
| 1.86
|  |
 |
7qky
|
Lövestam et al., 2022
|
Tau (266-391)(297-391)
| Recombinant, CuCl2, filament type 12a
| 309-360, 305-335
| cryoEM
| 2.83
|  |
 |
7qkf
|
Lövestam et al., 2022
|
Tau 4R
| Recombinant, Heparin Induced, Snake Polymorph
| 272-330
| cryoEM
| 3.3
|  |
 |
6qjh
|
Zhang et al., 2019
|
Tau 4R
| Recombinant, Heparin Induced, Twister Polymorph
| 274-292, 304-321
| cryoEM
| 3.3
|  |
 |
6qjm
|
Zhang et al., 2019
|
Tau 4R
| Recombinant, Heparin Induced, Jagged Polymorph
| 274-290, 304-321
| cryoEM
| 3.5
|  |
 |
6qjp
|
Zhang et al., 2019
|
Tau (258-391)
| Recombinant, heparan sulfate, 700 rpm, filament type 40a
| 275-328
| cryoEM
| 2.27
|  |
 |
7qk6
|
Lövestam et al., 2022
|
Tau (258-391)
| Recombinant, phosphoglycerate, 700 rpm, filament type 39a
| 275-328
| cryoEM
| 3.36
|  |
 |
7qkg
|
Lövestam et al., 2022
|
Tau (266-391) S356D
| Recombinant, KCl, filament type 44a
| 275-328
| cryoEM
| 2.32
|  |
 |
7qkw
|
Lövestam et al., 2022
|
Tau (244-391)
| Recombinant, Na4P2O7, filament type 20a
| 275-324
| cryoEM
| 2.95
|  |
 |
7ql2
|
Lövestam et al., 2022
|
Tau (258-391)
| Recombinant, 700 rpm, filament type 38a
| 270-330
| cryoEM
| 2.44
|  |
 |
7qk3
|
Lövestam et al., 2022
|
Tau (266-391) S356D
| Recombinant, NaCl, filament type 45a
| 274-328
| cryoEM
| 2.66
|  |
 |
7qkm
|
Lövestam et al., 2022
|
Tau 3R
| Recombinant, Heparin Induced
| 272-274,306-330
| cryoEM
| 3.5
|  |
 |
6qjq
|
Zhang et al., 2019
|
Tau (258-391)
| Recombinant, sodium azide, filament type 41a
| 277-317
| cryoEM
| 3.17
|  |
 |
7qkh
|
Lövestam et al., 2022
|
Tau (305-379)
| Recombinant, filament type 27a
| 307-317
| cryoEM
| 2.65
|  |
 |
7qkz
|
Lövestam et al., 2022
|
TDP-43 (247-257)
|
synthetic
|
247-257
|
cryoEM
|
3.7
|
 |
 |
5w7v
|
Guenther et al., 2018
|
TDP-43 (311-360)
| Recombinant
| 312-347
| cryoEM
| 3.8
|  |
 |
6n37
|
Cao et al., 2019
|
TDP-43 (311-360)
| Recombinant
| 312-352
| cryoEM
| 3.8
|  |
 |
6n3b
|
Cao et al., 2019
|
TDP-43 (311-360)
| Recombinant
| 311-360
| cryoEM
| 3.3
|  |
 |
6n3a
|
Cao et al., 2019
|
TDP-43 A315E (286-331)
| Recombinant
| 288-319
| cryoEM
| 3.3
|  |
 |
6n3c
|
Cao et al., 2019
|
TDP-43 Low Complexity Domain (267-414)
|
Recombinant
|
276-414
|
cryoEM
|
3.2
|
 |
 |
7kwz
|
Li et al., 2021
|
TDP-43 ALS and FTLD Filament
| Extracted from Patient with Amyotrophic Lateral Sclerosis and Fronto-temporal Lobar Degeneration
| 282-360
| cryoEM
| 2.59
|  |
 |
7py2
|
Arseni et al., 2021
|
TMEM106B Polymorph 1
| Extracted from Patient with Fronto-temporal Lobar Degeneration, Type C
| 120-254
| cryoEM
| 2.90
|  |
 |
7saq
|
Jiang et al., 2022
|
TMEM106B Fold I
| Extracted from Patient with Alzheimer's Disease, case 1
| 120-254
| cryoEM
| 2.64
|  |
 |
7qvc
|
Schweighauser et al., 2022
|
TMEM106B Fold II-a
| Extracted from Patient with Multiple System Atrophy, case 19
| 120-254
| cryoEM
| 3.38
|  |
 |
7qwg
|
Schweighauser et al., 2022
|
TMEM106B Fold II-b
| Extracted from Patient with Multiple System Atrophy, case 19
| 120-254
| cryoEM
| 3.47
|  |
 |
7qwl
|
Schweighauser et al., 2022
|
TMEM106B Fold III
| Extracted from Patient with Multiple System Atrophy, case 17
| 120-254
| cryoEM
| 2.76
|  |
 |
7qwm
|
Schweighauser et al., 2022
|
TMEM106B singlet filament
| Extracted from Patient with Progressive Supranuclear Palsy, case 2
| 120-254
| cryoEM
| 3.00
|  |
 |
7u10
|
Chang et al., 2022
|
TMEM106B singlet filament
| Extracted from Patient with Fronto-temporal Lobar Degeneration, Type A, case 1
| 120-254
| cryoEM
| 3.20
|  |
 |
7u11
|
Chang et al., 2022
|
TMEM106B singlet filament
| Extracted from Patient with Fronto-temporal Lobar Degeneration, Type A, case 2
| 120-254
| cryoEM
| 3.50
|  |
 |
7u12
|
Chang et al., 2022
|
TMEM106B singlet filament
| Extracted from Patient with Fronto-temporal Lobar Degeneration, Type A, case 4
| 120-254
| cryoEM
| 2.90
|  |
 |
7u13
|
Chang et al., 2022
|
TMEM106B singlet filament
| Extracted from Patient with Fronto-temporal Lobar Degeneration, Type C, case 8
| 120-254
| cryoEM
| 4.50
|  |
 |
7u14
|
Chang et al., 2022
|
TMEM106B singlet filament
| Extracted from Patient with Fronto-temporal Lobar Degeneration, Type B, case 7
| 120-254
| cryoEM
| 3.00
|  |
 |
7u15
|
Chang et al., 2022
|
TMEM106B singlet filament
| Extracted from Patient with Fronto-temporal Lobar Degeneration, Type A, all cases combined
| 120-254
| cryoEM
| 2.70
|  |
 |
7u16
|
Chang et al., 2022
|
TMEM106B T185S singlet filament
| Extracted from Patient with Fronto-temporal Lobar Degeneration, Type B, all cases combined
| 120-254
| cryoEM
| 3.00
|  |
 |
7u17
|
Chang et al., 2022
|
TMEM106B T185S singlet filament
| Extracted from Patient with Fronto-temporal Lobar Degeneration, Type A, all cases combined
| 120-254
| cryoEM
| 2.70
|  |
 |
7u18
|
Chang et al., 2022
|
TMEM106B
| Extracted from brain of 101 year old human with no diagnosed disease
| 120-254
| cryoEM
| 3.40
|  |
 |
7x83
|
Fan et al., 2022
|
TMEM106B
| Extracted from brain of patient with Parkinsons Disease Dementia
| 120-254
| cryoEM
| 3.00
|  |
 |
7x84
|
Fan et al., 2022
|
TMEM106B Polymorph 2
| Extracted from Patient with Fronto-temporal Lobar Degeneration, Type C
| 120-254
| cryoEM
| 3.20
|  |
 |
7sar
|
Jiang et al., 2022
|
TMEM106B Fold I-d
| Extracted from Patient with Multiple System Atrophy, case 18
| 120-254
| cryoEM
| 3.64
|  |
 |
7qvf
|
Schweighauser et al., 2022
|
TMEM106B Polymorph 3
| Extracted from Patient with Fronto-temporal Lobar Degeneration, Type C
| 120-254
| cryoEM
| 3.70
|  |
 |
7sas
|
Jiang et al., 2022
|
Transthyretin, V30M
|
Extracted from heart of a human with hereditary V30M ATTR Amyloidosis
|
11-35, 57-123
|
cryoEM
|
3.0
|
 |
 |
6sdz
|
Schmidt et al., 2019
|
Transthyretin, wildtype
| Extracted from the heart a Senile Systemic Amyloidosis Patient
| 11-35, 57-123
| cryoEM
| 2.78
|  |
 |
8ade
|
Steinebrei et al., 2022
|
Transthyretin, V30M
| Extracted from the Vitreous Body of the Eye of an Amyloid Transthyretin Amyloidosis (ATTR) Patient
| 11-35, 57-123
| cryoEM
| 3.22
|  |
 |
7ob4
|
Iakovleva et al., 2021
|
